PULSUS brings in a new spin on conferences by presenting the latest scientific improvements in your field. Listen to motivating keynotes from thought leaders or rub elbows with pioneers across the globe. Rome all set for an amazing event as PULSUS proudly presents the “3rd World Congress on Advanced Biomaterials and Tissue Engineering scheduled during August 26-27, 2019 at Madrid, Spain”.
The aim of this conference is to learn and share knowledge in Advanced Biomaterials and Tissue Engineering research. Leading Biologist, Biochemist, Tissue engineers, Material Science Professionals, Health Care specialist, Students and other professionals share their research work at Advanced Biomaterials 2018.
Biomaterials are those materials that can be it natural or synthetic, alive or lifeless, and usually made of multiple components that interact with biological systems. Biomaterials are often used in medical applications to augment or replace a natural function. The most novel topics of the biomaterials field are studied in latest literature: Testing of biomaterials, biostability, mechanisms of degradation, bio-and hemocompatibility of materials, sterilization of biomedical devices, cell-biomaterial interactions, drug delivery via biodegradable vehicles, hard and soft tissue augmentation, implants, dental applications and bone cements, biomedical instrumentation and imaging
Tissue engineering integrates biological components, such as cells and growth factors, with engineering principles and synthetic materials. Substitute tissues can be produced by first seeding human cells onto scaffolds, which may be made from collagen or from a biodegradable polymer. The scaffolds are then incubated in mediums containing growth factors, which stimulate the cells to grow and divide. As cells spread across the scaffold, the substitute tissue is formed. This tissue can be implanted into the human body, with the implanted scaffold eventually being either absorbed or dissolved.
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Session 1: Biomaterials
Biomaterials are those materials which are usually made of multiple components that interact with biological system. Biomaterials are normally used in medical application like drug delivery, therapeutics, and diagnostics to replace a natural function. The most commonly used biomaterials are polymers. All biomaterials meet certain criteria and regulatory requirements before they can be qualified for use in medical applications. Biomaterial Science has a broad scope that covers the fundamental science of biomaterials through to their biomedical applications.
Session 2: Tissue Engineering
Tissue engineering is an emerging field which involves biology, medicine, and engineering that is likely to revolutionize the ways we improve the health and quality of life for millions of people worldwide by restoring, maintaining, or enhancing tissue and organ function. In other words, tissue engineering is the development of artificial tissue and organ systems. The term regenerative medicine is often used synonymously with tissue engineering, although those involved in regenerative medicine place more emphasis on the use of stem cells to produce tissues
Session 3: Biomaterials for Stem Cell Therapy
Stem cell therapy is developing fast in the field of biomaterials. Combining stem cells with biomaterial scaffolds provides a promising response in engineering tissues and cellular delivery. Recent stem cell technologies have opened several ways for biomaterial research, such as developing disease models, drug development, tissue regeneration and development of functional organoids. The process also aim for development of adult stem cell-based tissue engineered biomaterial implants and organoids. This technique develops the cells to generate and use induced Pluripotent cells (iPS) from differentiated cells.
Session 4: Biomaterial for Implants
Implant or Implantation refers to insertion of biological material into the body for diagnosis or therapies. Biomaterial is generally used in dental Implants. There are different classification of dental implants they are based on Surface of implant, Implant design, the Type of material used and Attachment mechanism.
Session 5: Biomaterials for Drug Delivery system
Biomaterials play an important role in Drug delivery like biocompatible polymeric gene carriers have been introduced for treating diverse genetic and acquired diseases. The researchers are working on the biomaterial approaches to significantly improve outcomes of gene therapies for neurodegenerative disorders. The nanobiomaterial architecture is the basis for fabrication of novel integrated systems involving cells, growth factors, proteins, cytokines, drug molecules, and other biomolecules with the rationale of creating a universal, all-purpose nano-biomedical device for personalized therapies.
Session 6: 3D Bioprinting
Three-dimensional (3D) printing is most commonly used technique to fabricate scaffolds and devices for tissue engineering. The main aim of 3D printing is to provide patient-specific designs, high structural complexity and rapid on-demand fabrication at a low-cost. 3D printing techniques also require different materials like Thermoplastics; they are used for extrusion and commonly used in the 3D printing process. The two dominant thermoplastics are Acrylonitrile Butadiene Styrene (ABS) and Polylactid Acid (PLA). ABS is a fossil-based plasticand PLA a bio-based plastic.
Session 7: Recent trends in Tissue Engineering
Tissue engineering (TE) has given many emerging therapies that made a great success such as bone grafts, Histopathology, Tissue Biomarkers, valid approach to the bone regeneration/substitution. In contrast to classic biomaterial approach, TE is based on the understanding of tissue formation. Histopathology is the microscopic examination of tissue to study the diseases present in it. Tissue biomarker refers to the study of molecular or cellular structure of cell or tissues that is used to identify the disease caused due to the alterations present in the cells. The other most useful or important invention is the Photodynamic therapy. This is the form of light, sensitive chemical substance with molecular oxygen that is used to kills the foreign substance from the cells like Fungi, Bacteria and viruses.
Session 8: Tissue engineering in Artificial Organs
An Artificial organ is an engineered tissue that is implanted into human for interacting with living tissue to replace natural organ for restoring a patient’s state of living back to as normal as possible. The main purpose of this process is for supporting patient’s life. The Microchip or 'organs-on-chips' provide organ function and disease, and for applications such as toxicity tests of drug candidates. An alternative approach is to foster the ability of cells to self-assemble, in the hope that they will recapitulate actual organ development and reveal insights into the process.
Session 9: Regenerative Medicine
Regenerative medicine is the branch of medicine that develops methods to repair or replace damaged or diseased cells, organs or tissues. Regenerative medicine includes the generation and use of therapeutic stem cells, tissue engineering and the production of artificial organs. One of the greatest needs for regenerative therapy is in the field of whole organ replacement. The first bone marrow and solid-organ transplants were done years ago. But advances in developmental and cell biology, immunology, and other fields are new opportunities to refine existing regenerative therapies and develop new ones.
Session 10: Tissue Engineering Applications
There are many applications of Tissue engineering but majorly they are used in Organ Transplantation and Therapeutic Cloning like Bio Artificial liver device, Artificial pancreas, Artificial bladders, and Cartilage. When there is damage in our body cells or organs we use tissue engineering techniques to overcome the damage by replacing the old cell. There is wide range of Tissue Engineered product or materials which are used to cure diseases in human and save life.
Session 11: Anti Aging Medicine
Anti-Aging is also known as life extension science which aims to maintain or achieve this irrespective of chronological age i.e. to stay healthy and biologically efficient. It is the study of reversing the process of aging or slowing down of aging up to maximum lifespan. Anti-Aging Medicine is a clinical specialty based on advanced biomedical technologies and scientific research application mainly focused on the early detection of causes, prevention of occurrence , treatment of aging-related disease ,reversal of age-related dysfunction, disorders and diseases which is based on principles of sound and responsible medical care that are consistent with those innovative science and research applied in other preventive health specialties to prolong the healthy lifespan of tissues in humans.
Session 12: Bio-Imaging
Bioimaging (biological imaging) refers to any imaging technique used in life sciences and spans the full spectrum from molecule to man. An important sub-field is medical imaging, which refers to techniques and methods needed to create images of the human body (or parts and function thereof) for clinical purposes or medical science. Another field closely related to bioimaging is structural biology, a branch of molecular biology, biochemistry, and biophysics concerned with the spatial and temporal arrangement of biological macromolecules, (proteins and nucleic acids) and sub-cellular compartments.
Session 13: Advanced Materials
Biomaterials play an integral role in medicine today—restoring function and facilitating healing for people after injury or disease. Biomaterials may be natural or synthetic and are used in medical applications to support, enhance, or replace damaged tissue or a biological function. Bio-composites are formed by using resin and natural fibres. It can be non-wood natural fibres (rice, wheat, coconut, etc.) or wood fibres (magazines, soft and hardwoods). Metals are mainly a choice of biomaterials in fields of dental, orthopaedic, cardiac implants. As metals can lead to wear, corrosion, so surface coating and modification of metals are necessary for medical applications
Session 14: Biomaterials & Nanotechnology
Bionanomaterials are molecular materials composed partially or completely of biological molecules (such as antibodies, proteins/enzymes, DNA, RNA, lipids, oligosaccharides, viruses, and cells for example) and resulting in molecular structures having a nanoscale-dimension(s). The resulting bionanomaterials may have potential applications as novel fibres, sensors, adhesives, energy generating and/or harnessing materials, to mention just a few aspects. These types of systems can allow for fabrication of complex devices by self-assembly under mild experimental conditions and in an eco-friendly manner such as at room temperature and in aqueous conditions. Nano biomaterials are used for cancer treatment, regeneration, and polymeric one’s act as gene delivery systems. Nanofiber scaffolds are those fibres which are having diameters less than 100 nm. Nano scaffolding is a process to regrow tissue and bone, also used in stem cell expansion.
Session 15: Biophotonics
Biophotonics is the study of optical processes in biological systems, both those that occur naturally and in bioengineered materials. A particularly important aspect of this field is imaging and sensing cells and tissue. This includes injecting fluorescent markers into a biological system to track cell dynamics and drug delivery. Biophotonics covers a wide spectrum of biomedical application from understanding life processes to prevention, early recognition, and therapy of diseases.
Session 16: Tissue Biomarkers
A biomarker (BM) is a substance that is measured in a biological system as an indicator of exposure, effect, susceptibility, or clinical disease. Biomarkers not only characterize the function, quality, and safety/toxicity of a product (potency) but also help identify those patients or cohorts who would most likely benefit from such an innovative treatment modality (prediction or stratification) and allow efficacy in those patients who have been identified as responders to be monitored
Session 17: Tissue Replacement
Science of growing replacement organs and tissue in the lab to replace damaged or diseased tissue. The process usually starts with a three-dimensional structure called a scaffold that is used to support cells as they grow and develop. Skin, blood vessels, bladders, trachea, oesophagus, muscle and other types of tissue have been successfully engineered; and some of these tissues have already been used in treating human disease. Scientists at the Institute are working on a variety of strategies to engineer solid organs such as the liver, kidney, heart and pancreas